/*
 * DFA Biomarker Microsite — front end and editor.
 *
 * Every rule is scoped under :root so it outranks WordPress core block CSS
 * (e.g. `.wp-block-image img`, `.wp-block-group`) regardless of load order.
 * Values are the approved design's values; change them only with design sign-off.
 */

/* ---------- Tokens ---------- */
:root{
  --ivory:#F6F3EC;
  --ink:#15202D;
  --text:#2B3744;
  --slate:#5B6878;
  --blue:#2A62B5;
  --fill-neutral:#FBFAF6;
  --fill-blue:#E8EEF7;
  --rule:rgba(21,32,45,.16);
  --serif:'Lora',Georgia,serif;
  --sans:'Work Sans',system-ui,sans-serif;
  --gutter:clamp(20px,4vw,56px);
  --bleed:calc(-1 * (max(0px, (100vw - 1280px) / 2) + var(--gutter)));
  --ease:cubic-bezier(.2,.6,.2,1);
}

/* ---------- Base ---------- */
html{scroll-behavior:smooth;-webkit-text-size-adjust:100%}
body{margin:0;background:var(--ivory);color:var(--ink);font-family:var(--sans);-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}
a{color:var(--blue)}
a:hover{color:var(--ink)}
img{display:block;max-width:100%}
button{font:inherit}
sup{line-height:0}
h1,h2,h3,p,li{text-wrap:pretty}
:focus-visible{outline:2px solid var(--blue);outline-offset:3px}
:root .on-dark :focus-visible{outline-color:var(--ivory)}

/* Neutralise core block defaults inside the microsite (order matters: these come first). */
:root .wp-block-group{box-sizing:content-box}
:root :where(.dfa-main,.site-header,.site-footer) :where(p,h1,h2,h3,ol,ul,figure,blockquote){margin:0}
:root .wp-block-image{margin:0}
:root .wp-block-separator{border:0;margin:0;height:1px;background:var(--rule);opacity:1;width:auto}

/* Bleed photos intentionally run past the container (per the approved design); clip them here,
   not on body, so the viewport never becomes horizontally scrollable. */
:root main{display:block;overflow-x:clip}
:root .wrap{max-width:1280px;margin-left:auto;margin-right:auto;padding-inline:var(--gutter)}
:root .g12{display:grid;grid-template-columns:repeat(12,minmax(0,1fr));column-gap:24px}
:root :is(section,article)[id]{scroll-margin-top:72px}

/* Photo frames (core/image with class "frame") */
:root .frame{overflow:hidden}
:root .frame img{width:100%;height:100%;object-fit:cover}

/* Type roles */
:root .body{margin:0;font-size:clamp(17px,1.3vw,18px);line-height:1.65;color:var(--text)}
:root .body-lg{margin:0;font-size:clamp(17px,1.35vw,19px);line-height:1.6;color:var(--text)}
:root .body-sm{margin:0;font-size:17px;line-height:1.6;color:var(--text)}
:root .dek{margin:0;font-family:var(--serif);font-weight:400;font-size:clamp(22px,2.2vw,30px);line-height:1.25;color:var(--ink)}
:root .cat{font-size:15px;font-weight:500;color:var(--slate)}
:root .story-title{margin:10px 0 0;font-family:var(--serif);font-weight:600;font-size:clamp(30px,3vw,42px);line-height:1.1;letter-spacing:-.015em;color:var(--ink)}
:root .story-text .dek{margin-top:20px}
:root .story-text .body{margin-top:24px}
:root .wtm-label{font-weight:600;font-size:15px;color:var(--ink)}
:root .wtm{margin-top:36px;padding-top:22px;border-top:1px solid var(--ink)}
:root .wtm .body-sm{margin-top:10px}
:root .wtm-side{display:grid;grid-template-columns:140px 1fr;gap:12px 16px}
:root .wtm-side .wtm-label{padding-top:3px}
:root .wtm-side .body-sm{margin-top:0}
:root .src-ref a{color:var(--blue);text-decoration:none;font-size:12px;font-weight:600;margin-left:2px}
:root .src-ref a:hover{color:var(--ink)}

/* ---------- Header (template part) ---------- */
:root .site-header{position:sticky;top:var(--wp-admin--admin-bar--height,0px);z-index:50;background:var(--ink);border-bottom:1px solid rgba(246,243,236,.16)}
:root .bar{height:64px;display:flex;align-items:center;justify-content:space-between;gap:24px}
:root .logo a{display:flex;align-items:center;text-decoration:none}
:root .logo img{height:34px;width:auto}
:root .nav{display:flex;gap:34px}
:root .nav a{display:block;font-size:15px;font-weight:600;color:var(--ivory);text-decoration:none;padding:6px 0;border-bottom:2px solid transparent}
:root .nav a:hover{color:var(--ivory);border-bottom-color:var(--ivory)}
:root .wp-block-dfa-menu-toggle{display:contents}
:root .menu-btn{display:none;align-items:center;gap:8px;background:none;border:0;padding:10px 0;font-size:15px;font-weight:600;color:var(--ivory);cursor:pointer;min-height:44px}
:root .menu{position:absolute;left:0;right:0;top:100%;background:var(--ink);border-bottom:1px solid rgba(246,243,236,.16);padding:4px 20px 16px;display:flex;flex-direction:column}
:root .menu[hidden]{display:none}
:root .menu a{font-size:18px;font-weight:600;color:var(--ivory);text-decoration:none;padding:14px 0;border-top:1px solid rgba(246,243,236,.15)}

/* ---------- Opening ---------- */
:root .hero{display:grid;grid-template-columns:minmax(0,45fr) minmax(0,55fr);margin-top:-64px}
:root .hero-text{display:flex;flex-direction:column;justify-content:center;gap:30px;padding:120px 8% 72px max(var(--gutter), calc((100vw - 1280px) / 2 + 56px))}
:root .hero h1{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(40px,4.6vw,66px);line-height:1.04;letter-spacing:-.015em;color:var(--ink)}
:root .hero h1 .lead{display:block;font-weight:400;font-style:italic;font-size:clamp(18px,1.5vw,22px);line-height:1.35;letter-spacing:0;color:var(--slate);margin-bottom:20px}
:root .hero .body-lg{max-width:34em}
:root .byline{display:flex;align-items:center;gap:14px;font-size:14px;color:var(--slate)}
:root .byline::before{content:"";width:40px;height:1px;background:var(--ink)}
:root .hero-img{height:clamp(560px,88vh,900px)}
:root .hero-img img{object-position:50% 40%}

/* ---------- Why testing matters ---------- */
:root .why{padding-top:clamp(72px,9vw,120px)}
:root .explainer{display:grid;grid-template-columns:5fr 1fr 6fr;gap:32px 24px;align-items:start}
:root .explainer > :first-child{grid-column:1}
:root .explainer > :last-child{grid-column:3}
:root .statement{margin:24px 0 0;font-family:var(--serif);font-weight:400;font-size:clamp(26px,2.6vw,36px);line-height:1.2;letter-spacing:-.01em;color:var(--ink)}

:root .pair{display:grid;grid-template-columns:1fr 1fr;gap:24px}
:root .pair-first{margin-top:clamp(56px,7vw,96px)}
:root .box{padding:clamp(24px,3vw,36px) clamp(22px,3.2vw,40px) clamp(28px,3.4vw,40px);background:var(--fill-neutral);border:1px solid rgba(21,32,45,.18)}
:root .box-blue{background:var(--fill-blue);border-color:rgba(42,98,181,.35)}
:root .box svg{display:block}
:root .box-title{margin:22px 0 0;font-family:var(--sans);font-weight:600;font-size:20px;color:var(--ink)}
:root .box .dek{margin-top:10px}
:root .box .arrow{color:var(--slate);margin-right:12px}

:root .not-same{padding-top:clamp(72px,9vw,120px)}
:root .not-same h2{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(34px,4vw,54px);line-height:1.08;letter-spacing:-.015em;color:var(--ink);max-width:14em}
:root .not-same .intro{margin-top:28px;max-width:36em}
:root .not-same .pair{margin-top:56px}
:root .dots{display:grid;grid-template-columns:repeat(8,16px);gap:12px}
:root .dots span{width:16px;height:16px;border-radius:50%;box-sizing:border-box;border:1.5px solid rgba(21,32,45,.22)}
:root .dots span.t{border:2px solid var(--blue)}
:root .dots span.m{background:var(--slate)}
:root .dots-all span{border:1.5px solid var(--blue)}
:root .dots-all span.f{background:var(--blue)}
:root .caption-i{margin:20px 0 0;font-family:var(--serif);font-style:italic;font-size:18px;color:var(--slate)}
:root .box h3{margin:28px 0 0;font-weight:600;font-size:20px;color:var(--ink)}
:root .box .body{margin-top:12px}

:root .why-not{margin-top:clamp(80px,10vw,140px);align-items:start}
:root .why-not-text{grid-column:1/7;padding-top:40px}
:root .why-not h2{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(30px,3.2vw,44px);line-height:1.12;letter-spacing:-.01em;color:var(--ink)}
:root .why-not .body{margin-top:28px;max-width:32em}
:root .why-not-img{grid-column:7/13;margin-right:var(--bleed);height:clamp(360px,46vw,620px)}
:root .why-not-img img{object-position:60% 50%}

/* Timeline (dfa/timeline) */
:root .pathway{margin-top:clamp(80px,10vw,140px)}
:root .pathway .dek{letter-spacing:-.005em;max-width:32em}
:root .tl{margin-top:56px;position:relative;border-top:1px solid var(--rule);padding-top:40px}
:root .tl-ref{position:absolute;top:0;bottom:0;width:0;border-left:1px dashed rgba(42,98,181,.55)}
:root .tl-title{margin:0;font-family:var(--sans);font-weight:600;font-size:17px;color:var(--ink)}
:root .tl-title + .tl-row{margin-top:22px}
:root .tl-row + .tl-title{margin-top:28px}
:root .tl-row{position:relative;height:104px;list-style:none;padding:0;margin:0}
:root .tl-track{position:absolute;top:6px;height:1px;background:var(--ink)}
:root .tl-delay{position:absolute;top:3px;height:7px;background:rgba(91,104,120,.3)}
:root .tl-node{position:absolute;top:0;width:140px;transform:translateX(-50%);text-align:center}
:root .tl-node-start{width:max-content;max-width:90px;transform:none;text-align:left}
:root .tl-dot{width:13px;height:13px;border-radius:50%;background:var(--ivory);border:2px solid var(--ink);box-sizing:border-box;margin:0 auto}
:root .tl-node-start .tl-dot{margin:0}
:root .tl-label{margin-top:12px;font-size:15px;line-height:1.3;color:var(--ink);font-weight:500}
:root .tl-node.is-result .tl-dot{background:var(--blue);border-color:var(--blue)}
:root .tl-node.is-result .tl-label{color:var(--blue);font-weight:600}
:root .tl-caption{margin:12px 0 0;font-size:14px;line-height:1.5;color:var(--slate);max-width:40em}
:root .tl-more{margin:22px 0 0;font-size:16px}
:root .tl-more a{display:inline-block;font-size:16px;font-weight:600;color:var(--blue);text-decoration:none;border-bottom:1px solid var(--blue);padding-bottom:2px}
:root .tl-more a:hover{color:var(--ink)}

:root .access{display:grid;grid-template-columns:7fr 5fr;gap:32px 48px;margin-top:clamp(80px,10vw,140px);border-top:1px solid var(--ink);padding-top:40px;align-items:end}
:root .access h2{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(34px,4.4vw,60px);line-height:1.06;letter-spacing:-.02em;color:var(--ink)}

/* Pull quote (core/quote with class "pull"): the rule is the first grid cell. */
:root .pull{margin:clamp(80px,10vw,140px) 0 0;padding:0;display:grid;grid-template-columns:minmax(0,2fr) minmax(0,10fr);gap:24px 32px;align-items:start;overflow-wrap:normal}
:root .pull::before{content:"";display:block;height:1px;margin-top:.6em;background:var(--ink);font-size:clamp(32px,4.8vw,70px)}
:root .pull p{margin:0;font-family:var(--serif);font-style:italic;font-weight:400;font-size:clamp(32px,4.8vw,70px);line-height:1.08;letter-spacing:-.015em;color:var(--ink)}

/* ---------- Stories band ---------- */
:root .stories{margin-top:clamp(96px,12vw,160px);background:var(--ink);color:var(--ivory)}
:root .stories .wrap{padding-block:clamp(80px,10vw,140px)}
:root .stories-grid{display:grid;grid-template-columns:7fr 5fr;gap:40px 48px;align-items:end}
:root .stories h2{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(38px,5vw,68px);line-height:1.04;letter-spacing:-.02em;color:var(--ivory)}
:root .index{list-style:none;margin:0;padding:0;font-size:16px;line-height:1.3}
:root .index li{padding:14px 0;border-top:1px solid rgba(246,243,236,.25);display:flex;justify-content:space-between;gap:16px;text-wrap:wrap}
:root .index li:last-child{border-bottom:1px solid rgba(246,243,236,.25)}
:root .index a{color:var(--ivory);text-decoration:none}
:root .index a:hover{color:var(--ivory);text-decoration:underline;text-underline-offset:3px;text-decoration-thickness:1px}
:root .index .meta{color:rgba(246,243,236,.6);text-align:right}

/* ---------- Stories ---------- */
:root .story > .wrap{padding-top:clamp(80px,10vw,128px)}
:root .story-sep{margin-bottom:clamp(80px,10vw,128px)}

:root .s1{align-items:start}
:root .s1-img{grid-column:1/8;aspect-ratio:4/3}
:root .s1-img img{object-position:50% 50%}
:root .s1-text{grid-column:8/13;padding:8px 0 0 24px}

:root .s2{align-items:center}
:root .s2-text{grid-column:1/6;padding:24px 32px 24px 0}
:root .s2-img{grid-column:6/13;margin-right:var(--bleed);height:clamp(420px,52vw,720px)}
:root .s2-img img{object-position:62% 50%}

:root .s3-img{height:clamp(380px,68vh,760px);margin-top:clamp(80px,10vw,128px)}
:root .s3-img img{object-position:50% 18%}
:root .s3-panel{position:relative;margin-top:-170px;margin-left:33.33%;background:var(--ivory);padding:40px 0 0 48px}
:root .s3-panel .body{max-width:36em}
:root .split{display:grid;grid-template-columns:1fr 1fr;margin-top:56px;border-top:1px solid var(--ink)}
:root .split > :first-child{padding:28px 48px 36px 0}
:root .split > :last-child{padding:28px 0 36px 48px;border-left:1px solid var(--rule)}
:root .split-label{font-size:16px;font-weight:600;color:var(--slate)}
:root .split-text{margin:12px 0 0;font-family:var(--serif);font-size:clamp(22px,2.4vw,32px);line-height:1.22;color:var(--ink)}
:root .split > :last-child .split-text{color:var(--blue)}
:root .s3-wtm{padding-top:22px;border-top:1px solid var(--ink);display:grid;grid-template-columns:4fr 8fr;gap:12px 48px}
:root .s3-wtm .wtm-label{padding-top:3px}
:root .s3-wtm .body-sm{max-width:40em}

:root .s4{align-items:start}
:root .s4-img{grid-column:1/6;aspect-ratio:3/4}
:root .s4-img img{object-position:50% 62%}
:root .s4-text{grid-column:7/12;padding-top:48px}

:root .dollar{color:var(--blue);font-weight:600}

/* ---------- Data spread ---------- */
:root .data{margin-top:clamp(96px,12vw,160px);border-top:1px solid var(--ink)}
:root .data > .wrap{padding-top:clamp(48px,5vw,64px)}
:root .data h2{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(32px,3.8vw,52px);line-height:1.08;letter-spacing:-.015em;color:var(--ink);max-width:16em}
:root .spread{display:grid;grid-template-columns:repeat(12,minmax(0,1fr));margin-top:48px;border-top:1px solid var(--rule)}
:root .panel{display:flex;flex-direction:column}
:root .panel-l{padding:48px 56px 56px 0;border-right:1px solid var(--rule)}
:root .panel-r{padding:48px 0 56px 56px}
:root .p1{grid-column:1/8;justify-content:space-between;gap:40px}
:root .p2{grid-column:8/13;gap:28px}
:root .p3{grid-column:1/7;gap:32px}
:root .p4{grid-column:7/13;gap:32px}
:root .spread-rule{grid-column:1/-1}
:root .num{font-weight:600;font-size:clamp(56px,6vw,84px);line-height:.95;letter-spacing:-.035em;color:var(--ink)}
:root .num-xl{font-size:clamp(96px,11vw,172px);letter-spacing:-.04em}
:root .num-dek{margin:14px 0 0;font-family:var(--serif);font-size:clamp(20px,1.8vw,24px);line-height:1.25;color:var(--ink)}
:root .p1 .dek{margin-top:20px}
/* Plain wrapping where the approved design didn't balance lines (labels that were divs there are paragraphs here). */
:root :is(.num-dek,.p1 .dek,.tl-caption,.caption-i,.byline,.tl-more,.cat,.wtm-label,.split-label,.d-cat,.num,.box-title,.copyright,.nav p){text-wrap:wrap}
:root .d-cat{display:flex;align-items:center;gap:10px;font-size:14px;font-weight:500;color:var(--slate);margin-bottom:10px}
:root .d-cat::before{content:"";width:16px;height:2px;background:var(--blue);flex:none}
:root .p1 .body-sm{max-width:30em}
:root .branch{width:100%;max-width:380px;height:auto;display:block;overflow:visible}
:root .branch text{font-family:var(--sans);font-size:12px}

/* Duration bars (dfa/duration-bars) */
:root .bars{display:flex;flex-direction:column;gap:18px}
:root .bar-head{display:flex;justify-content:space-between;gap:12px;font-size:14px;color:var(--slate);margin-bottom:8px}
:root .bar-head b{color:var(--ink);font-weight:600;flex:none}
:root .track{height:14px;background:rgba(21,32,45,.07)}
:root .fill{height:100%;background:var(--slate)}
:root .fill-blue{background:var(--blue)}
:root .axis{position:relative;height:20px;font-size:12px;color:var(--slate)}
:root .axis i{position:absolute;top:0;width:1px;height:6px;background:rgba(21,32,45,.3)}
:root .axis span{position:absolute;top:8px}
:root .axis span.mid{left:50%;transform:translateX(-50%)}
:root .axis span.end{right:0}

/* ---------- Sources ---------- */
:root .sources{margin-top:clamp(96px,12vw,160px);border-top:1px solid var(--ink)}
:root .sources > .wrap{padding-top:48px}
:root .sources-grid{display:grid;grid-template-columns:4fr 8fr;gap:24px 48px;align-items:start}
:root .sources h2{margin:0;font-family:var(--serif);font-weight:500;font-size:clamp(30px,3vw,40px);line-height:1.1;color:var(--ink)}
:root .src{list-style:none;margin:0;padding:0;counter-reset:src}
:root .src li{counter-increment:src;padding:22px 0;border-top:1px solid var(--rule);display:grid;grid-template-columns:40px 1fr;gap:12px;font-size:16px;line-height:1.6;color:var(--text)}
:root .src li::before{content:counter(src);font-family:var(--serif);font-size:20px;color:var(--blue);line-height:1.3}
:root .src li:first-child{padding:0 0 22px;border-top:0}

/* ---------- Footer (template part) ---------- */
:root .site-footer{margin-top:clamp(72px,9vw,112px);border-top:1px solid var(--rule)}
:root .site-footer .wrap{padding-top:36px;padding-bottom:56px;display:flex;flex-wrap:wrap;justify-content:space-between;align-items:center;gap:20px 32px}
:root .site-footer .logo img{height:56px;width:auto}
:root .copyright{font-size:14px;color:var(--slate)}

/* ---------- Motion (front end only: the .motion class is set by an inline head script) ---------- */
@media (prefers-reduced-motion:no-preference){
  :root.motion .reveal{opacity:0;transform:translateY(18px);transition:opacity .8s var(--ease),transform .8s var(--ease)}
  :root.motion .reveal.is-in{opacity:1;transform:none}
  :root.motion .bars .fill{transform:scaleX(0);transform-origin:left center;transition:transform 1.2s cubic-bezier(.2,.7,.2,1) .15s}
  :root.motion .bars .fill.is-in{transform:scaleX(1)}
  :root.motion .frame img{opacity:0;transform:scale(1.03);transition:opacity 1s ease,transform 1.6s var(--ease)}
  :root.motion .frame.is-in img{opacity:1;transform:none}
}
@media (prefers-reduced-motion:reduce){html{scroll-behavior:auto}}

/* ---------- 768–1023 ---------- */
@media (max-width:1023px){
  :root .s3-panel{margin-left:16%;margin-top:-120px}
}

/* ---------- ≤767 ---------- */
@media (max-width:767px){
  :root .nav{display:none}
  :root .menu-btn{display:inline-flex}

  :root .hero{grid-template-columns:1fr}
  :root .hero-img{order:-1;height:74vw}
  :root .hero-text{padding:40px 20px 0;gap:22px}

  :root :is(.explainer,.pair,.access,.pull,.stories-grid,.split,.s3-wtm,.sources-grid,.wtm-side){grid-template-columns:1fr}
  :root .explainer > *{grid-column:auto!important}
  :root .split > :last-child{border-left:0;padding-left:0;border-top:1px solid var(--rule);padding-top:28px;margin-top:28px}

  :root .g12{grid-template-columns:1fr}
  :root .g12 > *{grid-column:1/-1!important;padding-left:0!important;padding-right:0!important}
  :root .g12 > .frame{order:-1;margin-bottom:28px}
  :root :is(.why-not-img,.s2-img){margin-left:-20px;margin-right:-20px}

  :root .s3-panel{margin:0;padding:28px 0 0}

  :root .spread > *{grid-column:1/-1!important;border-right:0!important;padding-left:0!important;padding-right:0!important;border-top:1px solid var(--rule)}
  :root .spread > :first-child{border-top:0}
  :root .spread-rule{display:none}

  :root .tl-row{height:auto;display:flex;flex-direction:column;gap:16px;margin-top:16px!important}
  :root :is(.tl-track,.tl-delay,.tl-ref){display:none}
  :root :is(.tl-node,.tl-node-start){position:static;transform:none;width:auto;max-width:none;text-align:left;display:flex;align-items:center;gap:14px}
  :root :is(.tl-dot,.tl-node-start .tl-dot){margin:0;flex:none}
  :root .tl-label{margin-top:0}
}
@media (min-width:768px){:root .menu{display:none!important}}

@media print{
  :root .site-header{position:static}
  :root.motion :is(.reveal,.frame img,.bars .fill){opacity:1!important;transform:none!important}
}

/* ---------- Secondary pages (index, 404, "Page with title") ---------- */
:root .plain{padding-top:clamp(72px,9vw,120px)}
:root .plain-title{margin:0 0 28px;font-family:var(--serif);font-weight:500;font-size:clamp(34px,4vw,54px);line-height:1.08;letter-spacing:-.015em;color:var(--ink);max-width:16em}
:root .plain-title a{color:inherit;text-decoration:none}
:root .plain-content{max-width:44em;font-size:clamp(17px,1.3vw,18px);line-height:1.65;color:var(--text)}
:root .plain-content :where(p,ul,ol){margin:0 0 1.2em}
:root .plain .wp-block-post-template{list-style:none;padding:0;display:grid;gap:56px}